Does MESNA Cause Pruritus? 32 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 32 reports of Pruritus have been filed in association with MESNA (mesna). This represents 0.7% of all adverse event reports for MESNA.
32
Reports of Pruritus with MESNA
0.7%
of all MESNA reports
5
Deaths
14
Hospitalizations
How Dangerous Is Pruritus From MESNA?
Of the 32 reports, 5 (15.6%) resulted in death, 14 (43.8%) required hospitalization, and 5 (15.6%) were considered life-threatening.
Is Pruritus Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MESNA. However, 32 reports have been filed with the FAERS database.
What Other Side Effects Does MESNA Cause?
Febrile neutropenia (707)
Pyrexia (352)
Off label use (299)
Cystitis haemorrhagic (294)
Disease progression (273)
Neutropenia (238)
Encephalopathy (226)
Vomiting (200)
Death (184)
Pancytopenia (179)
What Other Drugs Cause Pruritus?
DUPILUMAB (44,279)
ADAPALENE (12,072)
ADALIMUMAB (9,644)
AVOBENZONE\OCTISALATE\OCTOCRYLENE (9,439)
SECUKINUMAB (8,755)
ETANERCEPT (8,047)
METHOTREXATE (7,526)
LENALIDOMIDE (6,304)
TOCILIZUMAB (5,973)
RITUXIMAB (5,548)
Which MESNA Alternatives Have Lower Pruritus Risk?
MESNA vs METAMIZOLE
MESNA vs METARAMINOL
MESNA vs METAXALONE
MESNA vs METFORMIN
MESNA vs METFORMIN\PIOGLITAZONE