Does MESNA Cause Venoocclusive disease? 20 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 20 reports of Venoocclusive disease have been filed in association with MESNA (mesna). This represents 0.4% of all adverse event reports for MESNA.
20
Reports of Venoocclusive disease with MESNA
0.4%
of all MESNA reports
2
Deaths
3
Hospitalizations
How Dangerous Is Venoocclusive disease From MESNA?
Of the 20 reports, 2 (10.0%) resulted in death, 3 (15.0%) required hospitalization, and 2 (10.0%) were considered life-threatening.
Is Venoocclusive disease Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MESNA. However, 20 reports have been filed with the FAERS database.
What Other Side Effects Does MESNA Cause?
Febrile neutropenia (707)
Pyrexia (352)
Off label use (299)
Cystitis haemorrhagic (294)
Disease progression (273)
Neutropenia (238)
Encephalopathy (226)
Vomiting (200)
Death (184)
Pancytopenia (179)
What Other Drugs Cause Venoocclusive disease?
DEFIBROTIDE (576)
CYCLOPHOSPHAMIDE (457)
BUSULFAN (330)
FLUDARABINE (265)
CYTARABINE (240)
VINCRISTINE (239)
METHOTREXATE (237)
ETOPOSIDE (202)
DOXORUBICIN (174)
MELPHALAN (156)
Which MESNA Alternatives Have Lower Venoocclusive disease Risk?
MESNA vs METAMIZOLE
MESNA vs METARAMINOL
MESNA vs METAXALONE
MESNA vs METFORMIN
MESNA vs METFORMIN\PIOGLITAZONE