Does METHOTREXATE Cause Venoocclusive disease? 237 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 237 reports of Venoocclusive disease have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
237
Reports of Venoocclusive disease with METHOTREXATE
0.1%
of all METHOTREXATE reports
104
Deaths
64
Hospitalizations
How Dangerous Is Venoocclusive disease From METHOTREXATE?
Of the 237 reports, 104 (43.9%) resulted in death, 64 (27.0%) required hospitalization, and 34 (14.3%) were considered life-threatening.
Is Venoocclusive disease Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 237 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Venoocclusive disease?
DEFIBROTIDE (576)
CYCLOPHOSPHAMIDE (457)
BUSULFAN (330)
FLUDARABINE (265)
CYTARABINE (240)
VINCRISTINE (239)
ETOPOSIDE (202)
DOXORUBICIN (174)
MELPHALAN (156)
CYCLOSPORINE (132)
Which METHOTREXATE Alternatives Have Lower Venoocclusive disease Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA