Venoocclusive disease: Which Medications Cause It? (1,875 Reports Across 109 Drugs)
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Venoocclusive disease has been reported as an adverse event with 109 different drugs in the FDA's FAERS database, with 1,875 total reports. 615 of these reports resulted in death.The drugs most commonly associated with Venoocclusive disease are DEFIBROTIDE, CYCLOPHOSPHAMIDE, and BUSULFAN.
1,875
Total Reports
109
Drugs Involved
615
Deaths
498
Hospitalizations
31.7 yrs
Average Patient Age
36.7% / 63.3%
Female / Male
Which Drugs Cause Venoocclusive disease Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| DEFIBROTIDE | 576 | 15.4% | 125 | 79 | 21 |
| CYCLOPHOSPHAMIDE | 457 | 0.4% | 174 | 142 | 68 |
| BUSULFAN | 330 | 2.9% | 120 | 86 | 51 |
| FLUDARABINE | 265 | 1.1% | 110 | 64 | 18 |
| CYTARABINE | 240 | 0.5% | 108 | 77 | 49 |
| VINCRISTINE | 239 | 0.3% | 97 | 64 | 24 |
| METHOTREXATE | 237 | 0.1% | 104 | 64 | 34 |
| ETOPOSIDE | 202 | 0.4% | 70 | 51 | 31 |
| DOXORUBICIN | 174 | 0.2% | 87 | 36 | 13 |
| MELPHALAN | 156 | 1.0% | 45 | 25 | 26 |
| CYCLOSPORINE | 132 | 0.2% | 53 | 46 | 23 |
| MYCOPHENOLATE MOFETIL | 127 | 0.2% | 49 | 49 | 25 |
| INOTUZUMAB OZOGAMICIN | 109 | 4.7% | 44 | 37 | 19 |
| TACROLIMUS | 103 | 0.1% | 23 | 56 | 23 |
| CARBOPLATIN | 91 | 0.1% | 40 | 5 | 4 |
| THIOTEPA | 85 | 1.2% | 24 | 31 | 11 |
| LAPINE T-LYMPHOCYTE IMMUNE GLOBULIN | 76 | 0.8% | 32 | 13 | 7 |
| DEXAMETHASONE | 70 | 0.1% | 16 | 31 | 21 |
| MERCAPTOPURINE | 70 | 0.6% | 52 | 13 | 12 |
| DACTINOMYCIN | 68 | 2.4% | 18 | 7 | 4 |