Does METHADONE Cause Cardiotoxicity? 31 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 31 reports of Cardiotoxicity have been filed in association with METHADONE (METHADONE HYDROCHLORIDE). This represents 0.1% of all adverse event reports for METHADONE.
31
Reports of Cardiotoxicity with METHADONE
0.1%
of all METHADONE reports
18
Deaths
9
Hospitalizations
How Dangerous Is Cardiotoxicity From METHADONE?
Of the 31 reports, 18 (58.1%) resulted in death, 9 (29.0%) required hospitalization, and 4 (12.9%) were considered life-threatening.
Is Cardiotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHADONE. However, 31 reports have been filed with the FAERS database.
What Other Side Effects Does METHADONE Cause?
Drug dependence (5,739)
Toxicity to various agents (4,586)
Drug abuse (4,480)
Overdose (3,472)
Pain (2,754)
Death (2,716)
Emotional distress (2,388)
Drug withdrawal syndrome (2,127)
Foetal exposure during pregnancy (1,759)
Drug withdrawal syndrome neonatal (1,458)
What Other Drugs Cause Cardiotoxicity?
DOXORUBICIN (1,366)
CYCLOPHOSPHAMIDE (1,009)
TRASTUZUMAB (950)
VINCRISTINE (446)
FLUOROURACIL (425)
RITUXIMAB (389)
ETOPOSIDE (366)
CAPECITABINE (307)
TOCILIZUMAB (278)
PREDNISONE (277)
Which METHADONE Alternatives Have Lower Cardiotoxicity Risk?
METHADONE vs METHAMPHETAMINE
METHADONE vs METHENAMINE HIPPURATE
METHADONE vs METHIMAZOLE
METHADONE vs METHOCARBAMOL
METHADONE vs METHOHEXITAL