Does METHIMAZOLE Cause Agranulocytosis? 263 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 263 reports of Agranulocytosis have been filed in association with METHIMAZOLE (Methimazole). This represents 10.5% of all adverse event reports for METHIMAZOLE.
263
Reports of Agranulocytosis with METHIMAZOLE
10.5%
of all METHIMAZOLE reports
36
Deaths
199
Hospitalizations
How Dangerous Is Agranulocytosis From METHIMAZOLE?
Of the 263 reports, 36 (13.7%) resulted in death, 199 (75.7%) required hospitalization, and 51 (19.4%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
Yes, Agranulocytosis is listed as a known adverse reaction in the official FDA drug label for METHIMAZOLE.
What Other Side Effects Does METHIMAZOLE Cause?
Drug ineffective (305)
Hyperthyroidism (206)
Off label use (143)
Hypothyroidism (98)
Foetal exposure during pregnancy (85)
Neutropenia (78)
Condition aggravated (76)
Thyrotoxic crisis (75)
Drug-induced liver injury (73)
Product use in unapproved indication (67)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which METHIMAZOLE Alternatives Have Lower Agranulocytosis Risk?
METHIMAZOLE vs METHOCARBAMOL
METHIMAZOLE vs METHOHEXITAL
METHIMAZOLE vs METHOTREXATE
METHIMAZOLE vs METHOXSALEN
METHIMAZOLE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA