Does METHOTREXATE Cause Acidosis? 62 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 62 reports of Acidosis have been filed in association with METHOTREXATE (Methotrexate). This represents 0.0% of all adverse event reports for METHOTREXATE.
62
Reports of Acidosis with METHOTREXATE
0.0%
of all METHOTREXATE reports
38
Deaths
53
Hospitalizations
How Dangerous Is Acidosis From METHOTREXATE?
Of the 62 reports, 38 (61.3%) resulted in death, 53 (85.5%) required hospitalization, and 9 (14.5%) were considered life-threatening.
Is Acidosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 62 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Acidosis?
METFORMIN (427)
ACETAMINOPHEN (313)
EMPAGLIFLOZIN (179)
IBUPROFEN (162)
AMLODIPINE (133)
TRAMADOL (116)
TACROLIMUS (114)
MORPHINE (100)
QUETIAPINE (99)
PREDNISONE (94)
Which METHOTREXATE Alternatives Have Lower Acidosis Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA