Does METHOTREXATE Cause Agitation? 227 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 227 reports of Agitation have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
227
Reports of Agitation with METHOTREXATE
0.1%
of all METHOTREXATE reports
42
Deaths
151
Hospitalizations
How Dangerous Is Agitation From METHOTREXATE?
Of the 227 reports, 42 (18.5%) resulted in death, 151 (66.5%) required hospitalization, and 38 (16.7%) were considered life-threatening.
Is Agitation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 227 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Agitation?
DULOXETINE (3,630)
QUETIAPINE (1,845)
OLANZAPINE (1,695)
ARIPIPRAZOLE (1,329)
SERTRALINE (1,248)
RISPERIDONE (1,068)
PREGABALIN (963)
DIAZEPAM (943)
VENLAFAXINE (941)
LORAZEPAM (930)
Which METHOTREXATE Alternatives Have Lower Agitation Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA