Does METHOTREXATE Cause Arthritis? 5,746 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 5,746 reports of Arthritis have been filed in association with METHOTREXATE (Methotrexate). This represents 2.3% of all adverse event reports for METHOTREXATE.
5,746
Reports of Arthritis with METHOTREXATE
2.3%
of all METHOTREXATE reports
364
Deaths
1,927
Hospitalizations
How Dangerous Is Arthritis From METHOTREXATE?
Of the 5,746 reports, 364 (6.3%) resulted in death, 1,927 (33.5%) required hospitalization, and 541 (9.4%) were considered life-threatening.
Is Arthritis Listed in the Official Label?
Yes, Arthritis is listed as a known adverse reaction in the official FDA drug label for METHOTREXATE.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Arthritis?
ADALIMUMAB (8,592)
ETANERCEPT (6,054)
SECUKINUMAB (3,975)
TOFACITINIB (3,552)
ABATACEPT (3,129)
INFLIXIMAB (3,113)
TOCILIZUMAB (3,066)
RITUXIMAB (2,727)
PREDNISONE (2,595)
LEFLUNOMIDE (2,347)
Which METHOTREXATE Alternatives Have Lower Arthritis Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA