Does METHOTREXATE Cause Ataxia? 188 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 188 reports of Ataxia have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
188
Reports of Ataxia with METHOTREXATE
0.1%
of all METHOTREXATE reports
28
Deaths
85
Hospitalizations
How Dangerous Is Ataxia From METHOTREXATE?
Of the 188 reports, 28 (14.9%) resulted in death, 85 (45.2%) required hospitalization, and 8 (4.3%) were considered life-threatening.
Is Ataxia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 188 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Ataxia?
LAMOTRIGINE (535)
PHENYTOIN (406)
FINGOLIMOD (393)
LEVETIRACETAM (309)
GABAPENTIN (297)
CARBAMAZEPINE (272)
METRONIDAZOLE (260)
LITHIUM (250)
LORAZEPAM (235)
CLONAZEPAM (233)
Which METHOTREXATE Alternatives Have Lower Ataxia Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA