Does METHOTREXATE Cause Bicytopenia? 236 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 236 reports of Bicytopenia have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
236
Reports of Bicytopenia with METHOTREXATE
0.1%
of all METHOTREXATE reports
19
Deaths
136
Hospitalizations
How Dangerous Is Bicytopenia From METHOTREXATE?
Of the 236 reports, 19 (8.1%) resulted in death, 136 (57.6%) required hospitalization, and 42 (17.8%) were considered life-threatening.
Is Bicytopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 236 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Bicytopenia?
CARBOPLATIN (136)
LINEZOLID (119)
SULFAMETHOXAZOLE\TRIMETHOPRIM (81)
CISPLATIN (74)
RITUXIMAB (68)
GEMCITABINE (56)
ETOPOSIDE (55)
PEMBROLIZUMAB (51)
PACLITAXEL (49)
PEMETREXED (46)
Which METHOTREXATE Alternatives Have Lower Bicytopenia Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA