Does METHOTREXATE Cause Bone pain? 522 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 522 reports of Bone pain have been filed in association with METHOTREXATE (Methotrexate). This represents 0.2% of all adverse event reports for METHOTREXATE.
522
Reports of Bone pain with METHOTREXATE
0.2%
of all METHOTREXATE reports
2
Deaths
126
Hospitalizations
How Dangerous Is Bone pain From METHOTREXATE?
Of the 522 reports, 2 (0.4%) resulted in death, 126 (24.1%) required hospitalization, and 24 (4.6%) were considered life-threatening.
Is Bone pain Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 522 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Bone pain?
TERIPARATIDE (3,015)
DENOSUMAB (2,805)
PEGFILGRASTIM (2,266)
ZOLEDRONIC ACID (1,364)
ABALOPARATIDE (1,360)
LENALIDOMIDE (1,320)
PALBOCICLIB (1,199)
ADALIMUMAB (1,075)
LETROZOLE (891)
ETANERCEPT (766)
Which METHOTREXATE Alternatives Have Lower Bone pain Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA