Does METHOTREXATE Cause Coma? 335 Reports in FDA Database

Q: Does METHOTREXATE cause Coma?

335 reports of Coma have been filed with the FDA for METHOTREXATE, representing 0.1% of all METHOTREXATE adverse event reports.

Q: How dangerous is Coma from METHOTREXATE?

Of 335 reports, 58 (17.3%) resulted in death and 225 required hospitalization.

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According to the FDA Adverse Event Reporting System (FAERS), 335 reports of Coma have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.

335

Reports of Coma with METHOTREXATE

0.1%

of all METHOTREXATE reports

Deaths

225

Hospitalizations

How Dangerous Is Coma From METHOTREXATE?

Of the 335 reports, 58 (17.3%) resulted in death, 225 (67.2%) required hospitalization, and 133 (39.7%) were considered life-threatening.

Is Coma Listed in the Official Label?

Yes, Coma is listed as a known adverse reaction in the official FDA drug label for METHOTREXATE.

What Other Side Effects Does METHOTREXATE Cause?

Drug ineffective (70,142) Rheumatoid arthritis (29,254) Off label use (24,020) Pain (23,773) Drug intolerance (22,555) Arthralgia (21,831) Fatigue (19,885) Nausea (18,715) Joint swelling (17,657) Drug hypersensitivity (16,677)

What Other Drugs Cause Coma?

ACETAMINOPHEN (2,386) QUETIAPINE (2,267) DIAZEPAM (2,250) ALPRAZOLAM (2,042) PREGABALIN (1,941) TRAMADOL (1,708) ZOPICLONE (1,405) VENLAFAXINE (1,342) OXAZEPAM (1,256) BACLOFEN (1,133)

Which METHOTREXATE Alternatives Have Lower Coma Risk?

METHOTREXATE vs METHOXSALEN METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA METHOTREXATE vs METHYL ALCOHOL METHOTREXATE vs METHYLCOBALAMIN METHOTREXATE vs METHYLDOPA

METHOTREXATE Full Profile All Coma Reports All Drugs Causing Coma METHOTREXATE Demographics