Does METHOTREXATE Cause Crohn's disease? 2,869 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 2,869 reports of Crohn's disease have been filed in association with METHOTREXATE (Methotrexate). This represents 1.1% of all adverse event reports for METHOTREXATE.
2,869
Reports of Crohn's disease with METHOTREXATE
1.1%
of all METHOTREXATE reports
476
Deaths
1,069
Hospitalizations
How Dangerous Is Crohn's disease From METHOTREXATE?
Of the 2,869 reports, 476 (16.6%) resulted in death, 1,069 (37.3%) required hospitalization, and 421 (14.7%) were considered life-threatening.
Is Crohn's disease Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 2,869 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Crohn's disease?
ADALIMUMAB (15,916)
VEDOLIZUMAB (9,759)
INFLIXIMAB (7,777)
USTEKINUMAB (4,662)
CERTOLIZUMAB PEGOL (2,688)
PREDNISONE (1,518)
RISANKIZUMAB-RZAA (1,338)
AZATHIOPRINE (1,265)
MESALAMINE (1,235)
ETANERCEPT (1,167)
Which METHOTREXATE Alternatives Have Lower Crohn's disease Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA