Does METHOTREXATE Cause Cushingoid? 334 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 334 reports of Cushingoid have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
334
Reports of Cushingoid with METHOTREXATE
0.1%
of all METHOTREXATE reports
30
Deaths
104
Hospitalizations
How Dangerous Is Cushingoid From METHOTREXATE?
Of the 334 reports, 30 (9.0%) resulted in death, 104 (31.1%) required hospitalization, and 25 (7.5%) were considered life-threatening.
Is Cushingoid Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 334 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Cushingoid?
PREDNISONE (616)
PREDNISOLONE (351)
METHYLPREDNISOLONE (341)
AZATHIOPRINE (240)
BUDESONIDE (190)
DEXAMETHASONE (186)
RITUXIMAB (176)
MYCOPHENOLATE MOFETIL (174)
ADALIMUMAB (170)
TOFACITINIB (164)
Which METHOTREXATE Alternatives Have Lower Cushingoid Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA