Does METHOTREXATE Cause Deformity? 674 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 674 reports of Deformity have been filed in association with METHOTREXATE (Methotrexate). This represents 0.3% of all adverse event reports for METHOTREXATE.
674
Reports of Deformity with METHOTREXATE
0.3%
of all METHOTREXATE reports
13
Deaths
188
Hospitalizations
How Dangerous Is Deformity From METHOTREXATE?
Of the 674 reports, 13 (1.9%) resulted in death, 188 (27.9%) required hospitalization, and 15 (2.2%) were considered life-threatening.
Is Deformity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 674 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Deformity?
COPPER (1,530)
DOCETAXEL (928)
ETANERCEPT (623)
RANITIDINE (582)
ABATACEPT (556)
ADALIMUMAB (549)
TOCILIZUMAB (540)
LEFLUNOMIDE (507)
HYDROXYCHLOROQUINE (480)
RITUXIMAB (406)
Which METHOTREXATE Alternatives Have Lower Deformity Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA