Does METHOTREXATE Cause Delirium? 1,199 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,199 reports of Delirium have been filed in association with METHOTREXATE (Methotrexate). This represents 0.5% of all adverse event reports for METHOTREXATE.
1,199
Reports of Delirium with METHOTREXATE
0.5%
of all METHOTREXATE reports
691
Deaths
986
Hospitalizations
How Dangerous Is Delirium From METHOTREXATE?
Of the 1,199 reports, 691 (57.6%) resulted in death, 986 (82.2%) required hospitalization, and 764 (63.7%) were considered life-threatening.
Is Delirium Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 1,199 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Delirium?
OXYCODONE (1,378)
QUETIAPINE (1,279)
PREDNISONE (1,088)
ACETAMINOPHEN (1,056)
RITUXIMAB (1,034)
DICLOFENAC (982)
ADALIMUMAB (971)
HYDROXYCHLOROQUINE (912)
LORAZEPAM (881)
TOCILIZUMAB (864)
Which METHOTREXATE Alternatives Have Lower Delirium Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA