Does METHOTREXATE Cause Ear pain? 1,145 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,145 reports of Ear pain have been filed in association with METHOTREXATE (Methotrexate). This represents 0.5% of all adverse event reports for METHOTREXATE.
1,145
Reports of Ear pain with METHOTREXATE
0.5%
of all METHOTREXATE reports
194
Deaths
378
Hospitalizations
How Dangerous Is Ear pain From METHOTREXATE?
Of the 1,145 reports, 194 (16.9%) resulted in death, 378 (33.0%) required hospitalization, and 280 (24.5%) were considered life-threatening.
Is Ear pain Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 1,145 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Ear pain?
ETANERCEPT (1,234)
TOCILIZUMAB (1,104)
ADALIMUMAB (1,088)
ABATACEPT (948)
LEFLUNOMIDE (899)
CERTOLIZUMAB PEGOL (893)
GOLIMUMAB (866)
CHLORHEXIDINE (758)
ACETAMINOPHEN (724)
OXYCODONE (614)
Which METHOTREXATE Alternatives Have Lower Ear pain Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA