Does METHOTREXATE Cause Exposure during pregnancy? 2,222 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 2,222 reports of Exposure during pregnancy have been filed in association with METHOTREXATE (Methotrexate). This represents 0.9% of all adverse event reports for METHOTREXATE.
2,222
Reports of Exposure during pregnancy with METHOTREXATE
0.9%
of all METHOTREXATE reports
768
Deaths
952
Hospitalizations
How Dangerous Is Exposure during pregnancy From METHOTREXATE?
Of the 2,222 reports, 768 (34.6%) resulted in death, 952 (42.8%) required hospitalization, and 976 (43.9%) were considered life-threatening.
Is Exposure during pregnancy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 2,222 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Exposure during pregnancy?
ADALIMUMAB (4,556)
ACETAMINOPHEN (4,395)
INFLIXIMAB (3,636)
PREDNISONE (2,906)
HYDROXYCHLOROQUINE (2,610)
RITUXIMAB (2,468)
CETIRIZINE (2,435)
TOCILIZUMAB (2,342)
FOLIC ACID (2,318)
LEFLUNOMIDE (2,264)
Which METHOTREXATE Alternatives Have Lower Exposure during pregnancy Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA