Does METHOTREXATE Cause Extravasation? 11 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 11 reports of Extravasation have been filed in association with METHOTREXATE (Methotrexate). This represents 0.0% of all adverse event reports for METHOTREXATE.
11
Reports of Extravasation with METHOTREXATE
0.0%
of all METHOTREXATE reports
1
Deaths
4
Hospitalizations
How Dangerous Is Extravasation From METHOTREXATE?
Of the 11 reports, 1 (9.1%) resulted in death, 4 (36.4%) required hospitalization.
Is Extravasation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 11 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Extravasation?
IRON SUCROSE (122)
FERRIC CARBOXYMALTOSE (103)
DOXORUBICIN (92)
FLUOROURACIL (90)
OXALIPLATIN (90)
IOHEXOL (89)
RITUXIMAB (77)
CYCLOPHOSPHAMIDE (65)
NIVOLUMAB (55)
INFLIXIMAB (53)
Which METHOTREXATE Alternatives Have Lower Extravasation Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA