Does METHOTREXATE Cause Fibromyalgia? 4,131 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 4,131 reports of Fibromyalgia have been filed in association with METHOTREXATE (Methotrexate). This represents 1.6% of all adverse event reports for METHOTREXATE.
4,131
Reports of Fibromyalgia with METHOTREXATE
1.6%
of all METHOTREXATE reports
1,894
Deaths
2,276
Hospitalizations
How Dangerous Is Fibromyalgia From METHOTREXATE?
Of the 4,131 reports, 1,894 (45.8%) resulted in death, 2,276 (55.1%) required hospitalization, and 2,043 (49.5%) were considered life-threatening.
Is Fibromyalgia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 4,131 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Fibromyalgia?
ADALIMUMAB (4,457)
ETANERCEPT (3,589)
TOCILIZUMAB (3,363)
ABATACEPT (3,315)
LEFLUNOMIDE (3,221)
PREDNISONE (3,140)
RITUXIMAB (3,065)
HYDROXYCHLOROQUINE (3,048)
TOFACITINIB (3,031)
INFLIXIMAB (2,870)
Which METHOTREXATE Alternatives Have Lower Fibromyalgia Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA