Does METHOTREXATE Cause Fluid retention? 497 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 497 reports of Fluid retention have been filed in association with METHOTREXATE (Methotrexate). This represents 0.2% of all adverse event reports for METHOTREXATE.
497
Reports of Fluid retention with METHOTREXATE
0.2%
of all METHOTREXATE reports
186
Deaths
287
Hospitalizations
How Dangerous Is Fluid retention From METHOTREXATE?
Of the 497 reports, 186 (37.4%) resulted in death, 287 (57.7%) required hospitalization, and 164 (33.0%) were considered life-threatening.
Is Fluid retention Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 497 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Fluid retention?
AMBRISENTAN (3,927)
TREPROSTINIL (3,804)
MACITENTAN (2,861)
CALCIUM\DEXTROSE\MAGNESIUM\SODIUM\SODIUM (2,233)
SACUBITRIL\VALSARTAN (2,187)
ADALIMUMAB (1,193)
SELEXIPAG (1,044)
FUROSEMIDE (1,020)
LENALIDOMIDE (1,007)
EPOPROSTENOL (929)
Which METHOTREXATE Alternatives Have Lower Fluid retention Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA