Does METHOTREXATE Cause Generalised oedema? 161 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 161 reports of Generalised oedema have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
161
Reports of Generalised oedema with METHOTREXATE
0.1%
of all METHOTREXATE reports
23
Deaths
83
Hospitalizations
How Dangerous Is Generalised oedema From METHOTREXATE?
Of the 161 reports, 23 (14.3%) resulted in death, 83 (51.6%) required hospitalization, and 7 (4.3%) were considered life-threatening.
Is Generalised oedema Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 161 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Generalised oedema?
ADALIMUMAB (357)
ETANERCEPT (355)
IMATINIB (337)
ACETAMINOPHEN (276)
RITUXIMAB (261)
CYCLOPHOSPHAMIDE (248)
ESOMEPRAZOLE (248)
ATORVASTATIN (247)
PREGABALIN (247)
HUMAN IMMUNOGLOBULIN G (228)
Which METHOTREXATE Alternatives Have Lower Generalised oedema Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA