Does METHOTREXATE Cause Gout? 245 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 245 reports of Gout have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
245
Reports of Gout with METHOTREXATE
0.1%
of all METHOTREXATE reports
14
Deaths
75
Hospitalizations
How Dangerous Is Gout From METHOTREXATE?
Of the 245 reports, 14 (5.7%) resulted in death, 75 (30.6%) required hospitalization, and 11 (4.5%) were considered life-threatening.
Is Gout Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 245 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Gout?
LENALIDOMIDE (767)
ADALIMUMAB (530)
PEGLOTICASE (487)
FEBUXOSTAT (483)
ALLOPURINOL (447)
SACUBITRIL\VALSARTAN (387)
APIXABAN (354)
FUROSEMIDE (341)
RUXOLITINIB (307)
PREDNISONE (303)
Which METHOTREXATE Alternatives Have Lower Gout Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA