Does METHOTREXATE Cause Hypertensive crisis? 279 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 279 reports of Hypertensive crisis have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
279
Reports of Hypertensive crisis with METHOTREXATE
0.1%
of all METHOTREXATE reports
20
Deaths
149
Hospitalizations
How Dangerous Is Hypertensive crisis From METHOTREXATE?
Of the 279 reports, 20 (7.2%) resulted in death, 149 (53.4%) required hospitalization, and 2 (0.7%) were considered life-threatening.
Is Hypertensive crisis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 279 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Hypertensive crisis?
AMLODIPINE (456)
RAMIPRIL (326)
BEVACIZUMAB (213)
OXALIPLATIN (200)
VALSARTAN (199)
BISOPROLOL (190)
RITUXIMAB (185)
ADALIMUMAB (182)
CLONIDINE (172)
PACLITAXEL (159)
Which METHOTREXATE Alternatives Have Lower Hypertensive crisis Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA