Does METHOTREXATE Cause Hypoacusis? 284 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 284 reports of Hypoacusis have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
284
Reports of Hypoacusis with METHOTREXATE
0.1%
of all METHOTREXATE reports
4
Deaths
55
Hospitalizations
How Dangerous Is Hypoacusis From METHOTREXATE?
Of the 284 reports, 4 (1.4%) resulted in death, 55 (19.4%) required hospitalization, and 2 (0.7%) were considered life-threatening.
Is Hypoacusis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 284 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Hypoacusis?
SACUBITRIL\VALSARTAN (2,345)
TOFACITINIB (1,535)
INSULIN GLARGINE (1,406)
APIXABAN (1,249)
PREGABALIN (1,152)
ETANERCEPT (1,109)
INSULIN LISPRO (1,100)
ADALIMUMAB (948)
LENALIDOMIDE (938)
PALBOCICLIB (890)
Which METHOTREXATE Alternatives Have Lower Hypoacusis Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA