Does METHOTREXATE Cause Hypogonadism? 32 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 32 reports of Hypogonadism have been filed in association with METHOTREXATE (Methotrexate). This represents 0.0% of all adverse event reports for METHOTREXATE.
32
Reports of Hypogonadism with METHOTREXATE
0.0%
of all METHOTREXATE reports
0
Deaths
11
Hospitalizations
How Dangerous Is Hypogonadism From METHOTREXATE?
Of the 32 reports, 11 (34.4%) required hospitalization, and 14 (43.8%) were considered life-threatening.
Is Hypogonadism Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 32 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Hypogonadism?
FINASTERIDE (264)
OXYCODONE (40)
PROPECIA (35)
CYCLOPHOSPHAMIDE (29)
ACETAMINOPHEN\HYDROCODONE (26)
TESTOSTERONE (25)
ACETAMINOPHEN\OXYCODONE (24)
DENOSUMAB (24)
MORPHINE (24)
RISPERIDONE (22)
Which METHOTREXATE Alternatives Have Lower Hypogonadism Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA