Does METHOTREXATE Cause Joint injury? 1,091 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,091 reports of Joint injury have been filed in association with METHOTREXATE (Methotrexate). This represents 0.4% of all adverse event reports for METHOTREXATE.
1,091
Reports of Joint injury with METHOTREXATE
0.4%
of all METHOTREXATE reports
16
Deaths
409
Hospitalizations
How Dangerous Is Joint injury From METHOTREXATE?
Of the 1,091 reports, 16 (1.5%) resulted in death, 409 (37.5%) required hospitalization, and 65 (6.0%) were considered life-threatening.
Is Joint injury Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 1,091 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Joint injury?
ADALIMUMAB (1,966)
ETANERCEPT (1,294)
TOFACITINIB (846)
TOCILIZUMAB (712)
ABATACEPT (660)
PREDNISONE (621)
HYDROXYCHLOROQUINE (609)
INFLIXIMAB (603)
RITUXIMAB (531)
ANTIHEMOPHILIC FACTOR, HUMAN RECOMBINANT (511)
Which METHOTREXATE Alternatives Have Lower Joint injury Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA