Does METHOTREXATE Cause Liver disorder? 3,119 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 3,119 reports of Liver disorder have been filed in association with METHOTREXATE (Methotrexate). This represents 1.2% of all adverse event reports for METHOTREXATE.
3,119
Reports of Liver disorder with METHOTREXATE
1.2%
of all METHOTREXATE reports
924
Deaths
1,349
Hospitalizations
How Dangerous Is Liver disorder From METHOTREXATE?
Of the 3,119 reports, 924 (29.6%) resulted in death, 1,349 (43.3%) required hospitalization, and 1,007 (32.3%) were considered life-threatening.
Is Liver disorder Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 3,119 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Liver disorder?
ADALIMUMAB (2,502)
ETANERCEPT (1,990)
TOCILIZUMAB (1,853)
ABATACEPT (1,759)
RITUXIMAB (1,736)
ACETAMINOPHEN (1,723)
LEFLUNOMIDE (1,599)
TOFACITINIB (1,584)
HYDROXYCHLOROQUINE (1,514)
INFLIXIMAB (1,473)
Which METHOTREXATE Alternatives Have Lower Liver disorder Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA