Does METHOTREXATE Cause Malignant pleural effusion? 12 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 12 reports of Malignant pleural effusion have been filed in association with METHOTREXATE (Methotrexate). This represents 0.0% of all adverse event reports for METHOTREXATE.
12
Reports of Malignant pleural effusion with METHOTREXATE
0.0%
of all METHOTREXATE reports
5
Deaths
6
Hospitalizations
How Dangerous Is Malignant pleural effusion From METHOTREXATE?
Of the 12 reports, 5 (41.7%) resulted in death, 6 (50.0%) required hospitalization, and 4 (33.3%) were considered life-threatening.
Is Malignant pleural effusion Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 12 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Malignant pleural effusion?
PEMBROLIZUMAB (97)
CARBOPLATIN (65)
BEVACIZUMAB (64)
LETROZOLE (63)
NIVOLUMAB (61)
FULVESTRANT (58)
PACLITAXEL (58)
PALBOCICLIB (55)
CYCLOPHOSPHAMIDE (49)
OSIMERTINIB (46)
Which METHOTREXATE Alternatives Have Lower Malignant pleural effusion Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA