Does METHOTREXATE Cause Mania? 41 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 41 reports of Mania have been filed in association with METHOTREXATE (Methotrexate). This represents 0.0% of all adverse event reports for METHOTREXATE.
41
Reports of Mania with METHOTREXATE
0.0%
of all METHOTREXATE reports
0
Deaths
24
Hospitalizations
How Dangerous Is Mania From METHOTREXATE?
Of the 41 reports, 24 (58.5%) required hospitalization, and 1 (2.4%) were considered life-threatening.
Is Mania Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 41 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Mania?
ARIPIPRAZOLE (924)
QUETIAPINE (574)
LURASIDONE (544)
OLANZAPINE (520)
SERTRALINE (438)
RISPERIDONE (353)
LAMOTRIGINE (331)
LITHIUM (323)
VENLAFAXINE (319)
DULOXETINE (296)
Which METHOTREXATE Alternatives Have Lower Mania Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA