Does METHOTREXATE Cause Maternal exposure during pregnancy? 6,223 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 6,223 reports of Maternal exposure during pregnancy have been filed in association with METHOTREXATE (Methotrexate). This represents 2.5% of all adverse event reports for METHOTREXATE.
6,223
Reports of Maternal exposure during pregnancy with METHOTREXATE
2.5%
of all METHOTREXATE reports
1,482
Deaths
1,972
Hospitalizations
How Dangerous Is Maternal exposure during pregnancy From METHOTREXATE?
Of the 6,223 reports, 1,482 (23.8%) resulted in death, 1,972 (31.7%) required hospitalization, and 1,773 (28.5%) were considered life-threatening.
Is Maternal exposure during pregnancy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 6,223 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Maternal exposure during pregnancy?
CERTOLIZUMAB PEGOL (9,013)
ADALIMUMAB (7,518)
PREDNISONE (6,587)
RITUXIMAB (6,093)
INFLIXIMAB (6,061)
HYDROXYCHLOROQUINE (5,809)
FOLIC ACID (5,768)
TOCILIZUMAB (5,737)
LEFLUNOMIDE (5,643)
ABATACEPT (5,485)
Which METHOTREXATE Alternatives Have Lower Maternal exposure during pregnancy Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA