Does METHOTREXATE Cause Melaena? 160 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 160 reports of Melaena have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
160
Reports of Melaena with METHOTREXATE
0.1%
of all METHOTREXATE reports
42
Deaths
123
Hospitalizations
How Dangerous Is Melaena From METHOTREXATE?
Of the 160 reports, 42 (26.3%) resulted in death, 123 (76.9%) required hospitalization, and 30 (18.8%) were considered life-threatening.
Is Melaena Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 160 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Melaena?
ASPIRIN (2,001)
CLOPIDOGREL BISULFATE (1,547)
RIVAROXABAN (1,405)
APIXABAN (1,156)
WARFARIN (930)
IBUPROFEN (810)
DABIGATRAN ETEXILATE (700)
DICLOFENAC (576)
NAPROXEN (291)
FUROSEMIDE (272)
Which METHOTREXATE Alternatives Have Lower Melaena Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA