Does METHOTREXATE Cause Myocarditis? 118 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 118 reports of Myocarditis have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
118
Reports of Myocarditis with METHOTREXATE
0.1%
of all METHOTREXATE reports
14
Deaths
64
Hospitalizations
How Dangerous Is Myocarditis From METHOTREXATE?
Of the 118 reports, 14 (11.9%) resulted in death, 64 (54.2%) required hospitalization, and 9 (7.6%) were considered life-threatening.
Is Myocarditis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 118 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Myocarditis?
CLOZAPINE (1,702)
PEMBROLIZUMAB (1,060)
NIVOLUMAB (959)
IPILIMUMAB (475)
OLANZAPINE (425)
ATEZOLIZUMAB (372)
CARBOPLATIN (325)
QUETIAPINE (315)
MESALAMINE (272)
BEVACIZUMAB (230)
Which METHOTREXATE Alternatives Have Lower Myocarditis Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA