Does METHOTREXATE Cause Myopathy? 196 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 196 reports of Myopathy have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
196
Reports of Myopathy with METHOTREXATE
0.1%
of all METHOTREXATE reports
25
Deaths
77
Hospitalizations
How Dangerous Is Myopathy From METHOTREXATE?
Of the 196 reports, 25 (12.8%) resulted in death, 77 (39.3%) required hospitalization, and 25 (12.8%) were considered life-threatening.
Is Myopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 196 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Myopathy?
ATORVASTATIN (1,243)
SIMVASTATIN (624)
ROSUVASTATIN (596)
PREDNISONE (526)
METHYLPREDNISOLONE (321)
PREDNISOLONE (246)
DEXAMETHASONE (203)
METFORMIN (197)
MYCOPHENOLATE MOFETIL (177)
PRAVASTATIN (168)
Which METHOTREXATE Alternatives Have Lower Myopathy Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA