Does METHOTREXATE Cause Neutropenia? 4,363 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 4,363 reports of Neutropenia have been filed in association with METHOTREXATE (Methotrexate). This represents 1.7% of all adverse event reports for METHOTREXATE.
4,363
Reports of Neutropenia with METHOTREXATE
1.7%
of all METHOTREXATE reports
579
Deaths
1,732
Hospitalizations
How Dangerous Is Neutropenia From METHOTREXATE?
Of the 4,363 reports, 579 (13.3%) resulted in death, 1,732 (39.7%) required hospitalization, and 538 (12.3%) were considered life-threatening.
Is Neutropenia Listed in the Official Label?
Yes, Neutropenia is listed as a known adverse reaction in the official FDA drug label for METHOTREXATE.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Neutropenia?
CLOZAPINE (18,981)
CYCLOPHOSPHAMIDE (7,352)
LENALIDOMIDE (6,909)
RITUXIMAB (6,607)
PALBOCICLIB (6,423)
DEXAMETHASONE (6,050)
DOXORUBICIN (5,891)
CARBOPLATIN (5,314)
VINCRISTINE (4,982)
PACLITAXEL (4,553)
Which METHOTREXATE Alternatives Have Lower Neutropenia Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA