Does METHOTREXATE Cause Neutropenic sepsis? 411 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 411 reports of Neutropenic sepsis have been filed in association with METHOTREXATE (Methotrexate). This represents 0.2% of all adverse event reports for METHOTREXATE.
411
Reports of Neutropenic sepsis with METHOTREXATE
0.2%
of all METHOTREXATE reports
161
Deaths
228
Hospitalizations
How Dangerous Is Neutropenic sepsis From METHOTREXATE?
Of the 411 reports, 161 (39.2%) resulted in death, 228 (55.5%) required hospitalization, and 136 (33.1%) were considered life-threatening.
Is Neutropenic sepsis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 411 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Neutropenic sepsis?
CYCLOPHOSPHAMIDE (841)
CARBOPLATIN (757)
DEXAMETHASONE (684)
DOXORUBICIN (652)
RITUXIMAB (633)
VINCRISTINE (607)
ETOPOSIDE (569)
CISPLATIN (395)
DOCETAXEL (351)
PREDNISOLONE (343)
Which METHOTREXATE Alternatives Have Lower Neutropenic sepsis Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA