Does METHOTREXATE Cause Onychomycosis? 742 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 742 reports of Onychomycosis have been filed in association with METHOTREXATE (Methotrexate). This represents 0.3% of all adverse event reports for METHOTREXATE.
742
Reports of Onychomycosis with METHOTREXATE
0.3%
of all METHOTREXATE reports
387
Deaths
612
Hospitalizations
How Dangerous Is Onychomycosis From METHOTREXATE?
Of the 742 reports, 387 (52.2%) resulted in death, 612 (82.5%) required hospitalization, and 384 (51.8%) were considered life-threatening.
Is Onychomycosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 742 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Onychomycosis?
ADALIMUMAB (791)
RITUXIMAB (708)
TOCILIZUMAB (706)
ETANERCEPT (683)
INFLIXIMAB (630)
CERTOLIZUMAB PEGOL (629)
GOLIMUMAB (625)
ABATACEPT (615)
TOFACITINIB (601)
HYDROXYCHLOROQUINE (590)
Which METHOTREXATE Alternatives Have Lower Onychomycosis Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA