Does METHOTREXATE Cause Pancreatitis? 1,213 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,213 reports of Pancreatitis have been filed in association with METHOTREXATE (Methotrexate). This represents 0.5% of all adverse event reports for METHOTREXATE.
1,213
Reports of Pancreatitis with METHOTREXATE
0.5%
of all METHOTREXATE reports
221
Deaths
728
Hospitalizations
How Dangerous Is Pancreatitis From METHOTREXATE?
Of the 1,213 reports, 221 (18.2%) resulted in death, 728 (60.0%) required hospitalization, and 242 (20.0%) were considered life-threatening.
Is Pancreatitis Listed in the Official Label?
Yes, Pancreatitis is listed as a known adverse reaction in the official FDA drug label for METHOTREXATE.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Pancreatitis?
LIRAGLUTIDE (1,467)
DULAGLUTIDE (1,440)
SEMAGLUTIDE (1,374)
ADALIMUMAB (1,359)
INFLIXIMAB (948)
SITAGLIPTIN (922)
TIRZEPATIDE (906)
PREDNISONE (876)
AZATHIOPRINE (794)
ACETAMINOPHEN (615)
Which METHOTREXATE Alternatives Have Lower Pancreatitis Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA