Does METHOTREXATE Cause Pericarditis? 5,674 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 5,674 reports of Pericarditis have been filed in association with METHOTREXATE (Methotrexate). This represents 2.2% of all adverse event reports for METHOTREXATE.
5,674
Reports of Pericarditis with METHOTREXATE
2.2%
of all METHOTREXATE reports
1,805
Deaths
2,492
Hospitalizations
How Dangerous Is Pericarditis From METHOTREXATE?
Of the 5,674 reports, 1,805 (31.8%) resulted in death, 2,492 (43.9%) required hospitalization, and 2,256 (39.8%) were considered life-threatening.
Is Pericarditis Listed in the Official Label?
Yes, Pericarditis is listed as a known adverse reaction in the official FDA drug label for METHOTREXATE.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Pericarditis?
CETIRIZINE (5,494)
ABATACEPT (5,385)
PREDNISONE (5,377)
RITUXIMAB (5,360)
TOCILIZUMAB (5,320)
ADALIMUMAB (5,303)
LEFLUNOMIDE (5,282)
INFLIXIMAB (5,231)
FOLIC ACID (5,153)
HYDROXYCHLOROQUINE (5,125)
Which METHOTREXATE Alternatives Have Lower Pericarditis Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA