Does METHOTREXATE Cause Polyarthritis? 987 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 987 reports of Polyarthritis have been filed in association with METHOTREXATE (Methotrexate). This represents 0.4% of all adverse event reports for METHOTREXATE.
987
Reports of Polyarthritis with METHOTREXATE
0.4%
of all METHOTREXATE reports
28
Deaths
503
Hospitalizations
How Dangerous Is Polyarthritis From METHOTREXATE?
Of the 987 reports, 28 (2.8%) resulted in death, 503 (51.0%) required hospitalization, and 102 (10.3%) were considered life-threatening.
Is Polyarthritis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 987 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Polyarthritis?
ADALIMUMAB (864)
INFLIXIMAB (670)
ETANERCEPT (642)
TOCILIZUMAB (575)
HYDROXYCHLOROQUINE (562)
SULFASALAZINE (548)
ABATACEPT (546)
PREDNISONE (535)
NAPROXEN (442)
ANAKINRA (415)
Which METHOTREXATE Alternatives Have Lower Polyarthritis Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA