Does METHOTREXATE Cause Pregnancy? 661 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 661 reports of Pregnancy have been filed in association with METHOTREXATE (Methotrexate). This represents 0.3% of all adverse event reports for METHOTREXATE.
661
Reports of Pregnancy with METHOTREXATE
0.3%
of all METHOTREXATE reports
366
Deaths
471
Hospitalizations
How Dangerous Is Pregnancy From METHOTREXATE?
Of the 661 reports, 366 (55.4%) resulted in death, 471 (71.3%) required hospitalization, and 408 (61.7%) were considered life-threatening.
Is Pregnancy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 661 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Pregnancy?
VEDOLIZUMAB (1,567)
CERTOLIZUMAB PEGOL (920)
ETANERCEPT (816)
RITUXIMAB (736)
ADALIMUMAB (713)
FOLIC ACID (657)
INFLIXIMAB (657)
TOCILIZUMAB (647)
DICLOFENAC (641)
LEFLUNOMIDE (640)
Which METHOTREXATE Alternatives Have Lower Pregnancy Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA