Does METHOTREXATE Cause Pulmonary fibrosis? 2,912 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 2,912 reports of Pulmonary fibrosis have been filed in association with METHOTREXATE (Methotrexate). This represents 1.2% of all adverse event reports for METHOTREXATE.
2,912
Reports of Pulmonary fibrosis with METHOTREXATE
1.2%
of all METHOTREXATE reports
856
Deaths
1,472
Hospitalizations
How Dangerous Is Pulmonary fibrosis From METHOTREXATE?
Of the 2,912 reports, 856 (29.4%) resulted in death, 1,472 (50.5%) required hospitalization, and 871 (29.9%) were considered life-threatening.
Is Pulmonary fibrosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 2,912 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Pulmonary fibrosis?
ADALIMUMAB (2,277)
RITUXIMAB (2,192)
ETANERCEPT (1,926)
TOCILIZUMAB (1,886)
ABATACEPT (1,828)
HYDROXYCHLOROQUINE (1,740)
LEFLUNOMIDE (1,731)
PREDNISONE (1,692)
INFLIXIMAB (1,595)
SULFASALAZINE (1,428)
Which METHOTREXATE Alternatives Have Lower Pulmonary fibrosis Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA