Does METHOTREXATE Cause Pulmonary hypertension? 165 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 165 reports of Pulmonary hypertension have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
165
Reports of Pulmonary hypertension with METHOTREXATE
0.1%
of all METHOTREXATE reports
39
Deaths
80
Hospitalizations
How Dangerous Is Pulmonary hypertension From METHOTREXATE?
Of the 165 reports, 39 (23.6%) resulted in death, 80 (48.5%) required hospitalization, and 38 (23.0%) were considered life-threatening.
Is Pulmonary hypertension Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 165 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Pulmonary hypertension?
TREPROSTINIL (1,931)
MACITENTAN (1,505)
AMBRISENTAN (1,504)
SELEXIPAG (681)
EPOPROSTENOL (591)
SILDENAFIL (517)
BOSENTAN (504)
TADALAFIL (428)
RIOCIGUAT (411)
ADALIMUMAB (287)
Which METHOTREXATE Alternatives Have Lower Pulmonary hypertension Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA