Does METHOTREXATE Cause Pyelonephritis? 330 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 330 reports of Pyelonephritis have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
330
Reports of Pyelonephritis with METHOTREXATE
0.1%
of all METHOTREXATE reports
28
Deaths
206
Hospitalizations
How Dangerous Is Pyelonephritis From METHOTREXATE?
Of the 330 reports, 28 (8.5%) resulted in death, 206 (62.4%) required hospitalization, and 17 (5.2%) were considered life-threatening.
Is Pyelonephritis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 330 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Pyelonephritis?
TACROLIMUS (324)
RITUXIMAB (259)
MYCOPHENOLATE MOFETIL (235)
PREDNISONE (199)
PREDNISOLONE (186)
ADALIMUMAB (175)
TOCILIZUMAB (160)
DEXAMETHASONE (154)
INFLIXIMAB (154)
METHYLPREDNISOLONE (149)
Which METHOTREXATE Alternatives Have Lower Pyelonephritis Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA