Does METHOTREXATE Cause Rib fracture? 246 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 246 reports of Rib fracture have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
246
Reports of Rib fracture with METHOTREXATE
0.1%
of all METHOTREXATE reports
16
Deaths
168
Hospitalizations
How Dangerous Is Rib fracture From METHOTREXATE?
Of the 246 reports, 16 (6.5%) resulted in death, 168 (68.3%) required hospitalization, and 1 (0.4%) were considered life-threatening.
Is Rib fracture Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 246 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Rib fracture?
ADALIMUMAB (739)
LENALIDOMIDE (635)
DENOSUMAB (473)
EMTRICITABINE\TENOFOVIR DISOPROXIL (433)
ALENDRONATE (341)
ETANERCEPT (313)
PREDNISONE (289)
TOFACITINIB (286)
EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL (283)
CARBIDOPA\LEVODOPA (281)
Which METHOTREXATE Alternatives Have Lower Rib fracture Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA