Does METHOTREXATE Cause Spinal osteoarthritis? 345 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 345 reports of Spinal osteoarthritis have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
345
Reports of Spinal osteoarthritis with METHOTREXATE
0.1%
of all METHOTREXATE reports
12
Deaths
177
Hospitalizations
How Dangerous Is Spinal osteoarthritis From METHOTREXATE?
Of the 345 reports, 12 (3.5%) resulted in death, 177 (51.3%) required hospitalization, and 2 (0.6%) were considered life-threatening.
Is Spinal osteoarthritis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 345 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Spinal osteoarthritis?
ADALIMUMAB (813)
ALENDRONATE (454)
ETANERCEPT (227)
ZOMETA (166)
FOSAMAX (152)
EMTRICITABINE\TENOFOVIR DISOPROXIL (138)
RITUXIMAB (126)
PREDNISONE (123)
SECUKINUMAB (121)
PREGABALIN (115)
Which METHOTREXATE Alternatives Have Lower Spinal osteoarthritis Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA