Does METHOTREXATE Cause Stress fracture? 212 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 212 reports of Stress fracture have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
212
Reports of Stress fracture with METHOTREXATE
0.1%
of all METHOTREXATE reports
1
Deaths
47
Hospitalizations
How Dangerous Is Stress fracture From METHOTREXATE?
Of the 212 reports, 1 (0.5%) resulted in death, 47 (22.2%) required hospitalization.
Is Stress fracture Listed in the Official Label?
Yes, Stress fracture is listed as a known adverse reaction in the official FDA drug label for METHOTREXATE.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Stress fracture?
ALENDRONATE (837)
IBANDRONATE (346)
DENOSUMAB (281)
RISEDRONATE (196)
ADALIMUMAB (168)
ALENDRONATE\CHOLECALCIFEROL (137)
ETANERCEPT (115)
FOSAMAX (109)
PREDNISONE (91)
TERIPARATIDE (88)
Which METHOTREXATE Alternatives Have Lower Stress fracture Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA