Does METHOTREXATE Cause Surgery? 420 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 420 reports of Surgery have been filed in association with METHOTREXATE (Methotrexate). This represents 0.2% of all adverse event reports for METHOTREXATE.
420
Reports of Surgery with METHOTREXATE
0.2%
of all METHOTREXATE reports
4
Deaths
148
Hospitalizations
How Dangerous Is Surgery From METHOTREXATE?
Of the 420 reports, 4 (1.0%) resulted in death, 148 (35.2%) required hospitalization, and 3 (0.7%) were considered life-threatening.
Is Surgery Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 420 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Surgery?
ADALIMUMAB (3,506)
ETANERCEPT (2,977)
UPADACITINIB (2,037)
RISANKIZUMAB-RZAA (1,662)
SODIUM OXYBATE (1,554)
DUPILUMAB (1,540)
CERTOLIZUMAB PEGOL (1,322)
IBRUTINIB (1,204)
CALCIUM OXYBATE\MAGNESIUM OXYBATE\POTASSIUM OXYBATE\SODIUM OXYBATE (908)
INFLIXIMAB (769)
Which METHOTREXATE Alternatives Have Lower Surgery Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA