Does METHOTREXATE Cause Tuberculosis? 817 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 817 reports of Tuberculosis have been filed in association with METHOTREXATE (Methotrexate). This represents 0.3% of all adverse event reports for METHOTREXATE.
817
Reports of Tuberculosis with METHOTREXATE
0.3%
of all METHOTREXATE reports
37
Deaths
218
Hospitalizations
How Dangerous Is Tuberculosis From METHOTREXATE?
Of the 817 reports, 37 (4.5%) resulted in death, 218 (26.7%) required hospitalization, and 16 (2.0%) were considered life-threatening.
Is Tuberculosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 817 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Tuberculosis?
INFLIXIMAB (1,247)
ADALIMUMAB (1,047)
ETANERCEPT (632)
GOLIMUMAB (413)
CERTOLIZUMAB PEGOL (399)
SECUKINUMAB (396)
TOFACITINIB (301)
PREDNISONE (283)
ISONIAZID (261)
BUDESONIDE (241)
Which METHOTREXATE Alternatives Have Lower Tuberculosis Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA